August 2020. Adoption of electronic health records has increased physician documentation burden, raising concerns about physician burnout deriving from after-hours EHR use. We analyzed two years of longitudinal survey data of EHR users at a large health system, to compare physicians’ rates of reported off-hours use to other EHR users. 25% of physicians reported EHR use on days off, and 50% reported use in the evenings, compared to 5% and 41% of nurses, respectively. These findings suggest that the burden of after-hours EHR use falls primarily on physicians, however other EHR users also report after-hours and off-day EHR use.